Exploration of Bioactive Compounds, Toxicity and Activity of Sea Cucumber Stichopus horrens in Tagalaya and Tolonuo Villages, North Halmahera

Febrina Olivia Akerina; Kadek Intan Dwi Anggari

doi:10.52046/agrikan.v14i2.866

Febrina Olivia Akerina Universitas Hein Namotemo Tobelo
Kadek Intan Dwi Anggari Universitas Hein Namotemo

DOI: https://doi.org/10.52046/agrikan.v14i2.866

Keywords: Teripang kering, Tobelo, senyawa bioaktif, Stichopus horrens, toksisitas

Abstract

Sea cucumbers are marine invertebrates that have a high selling value and are even traded on the international market. Tagalaya and Tolonuo villages are villages in North Halmahera that have sea cucumber fishermen, and sell their processed sea cucumbers in dry form. This study aims to identify bioactive compounds, toxicity and antioxidant activity of sea cucumber extract Stichopus horrens obtained from Tagalaya Village and Tolonuo Village, North Halmahera. The results of the analysis showed that the highest yield of the extraction process was sea cucumber B which was 16.93%, the LC50 value ranged from 332.16 to 368.54 ppm which was included in the toxic category. The biochemical compounds found in both sea cucumber extracts are saponins. Sea cucumber extract showed no antioxidant activity

Author Biographies

Febrina Olivia Akerina, Universitas Hein Namotemo Tobelo

Program Studi Teknologi Hasil Perikanan, Fakultas Sains, Teknologi dan Kesehatan Universitas Hein Namotemo Tobelo, Indonesia

Kadek Intan Dwi Anggari, Universitas Hein Namotemo

Program Studi Teknologi Hasil Perikanan, Fakultas Sains, Teknologi dan Kesehatan Universitas Hein Namotemo Tobelo, Indonesia

References

Akerina, F. O. and Sangaji, J. (2019) ‘Analisis Fitokimia dan Toksisitas serta Aktivitas Antioksidan Beberapa Jenis Teripang di Desa Kakara, Halmahera Utara’, Agrikan: Jurnal Agribisnis Perikanan, 12(2), p. 188. doi: 10.29239/j.agrikan.12.2.188-196.

Bordbar, S., Anwar, F. and Saari, N. (2011) ‘High-Value Components and Bioactives from Sea Cucumbers for Functional Foods — A Review’, pp. 1761–1805. doi: 10.3390/md9101761.

Caulier, G. et al. (2011) ‘Review of saponin diversity in sea cucumbers belonging to the family Holothuriidae’, (July 2014).

Dwicahyani, T., Sumardianto and Rianingsih, L. (2018) ‘Uji Bioaktivitas Ekstrak Teripang Keling (Holothuria atra) Sebagai Antibakteri Staphylococcus aureus dan Escherichia coli’, Pengolahan dan Bioteknologi Hasil Perikanan, 7(1), pp. 15–24.

Van Dyck, S. et al. (2011) ‘The triterpene glycosides of Holothuria forskali: Usefulness and efficiency as a chemical defense mechanism against predatory fish’, Journal of Experimental Biology, 214(8), pp. 1347–1356. doi: 10.1242/jeb.050930.

Farouk, A. E. A., Ghouse, F. A. H. and Ridzwan, B. H. (2007) ‘New bacterial species isolated from Malaysian sea cucumbers with optimized secreted antibacterial activity’, American Journal of Biochemistry and Biotechnology, 3(2), pp. 64–69.

Gasango, H., Manu, G. D. and Tamanampo, J. F. W. S. (2013) ‘Struktur Komunitas Teripang ( Holothuroidea) di Pantai Desa Kakara Pulau Kecamatan Tobelo Kabupaten Tobelo’, 1(September), pp. 187–195.

Haediningrum, F. (2017) Aktivitas Antioksidan Ekstrak Metanol Dan Air Teripang Asap Secara in Vitro. Institut Pertanian Bogor.

Harborne, J. B. (1984) ‘Methods of Plant Analysis. In Phytochemical Methods’, in Phytochemical Methods, pp. 1–36. doi: https://doi.org/10.1007/978-94-009-5570-7_1.

Herliany, N. E., Nofridiansyah, E. and Sasongko, B. (2016) ‘Studi Pengolahan Teripang Kering’, Jurnal Enggano, 1(2), pp. 11–19.

Manoppo, E. S., Wewengkang, D. S. and Kojong, N. (2017) ‘Aktivitas Antibakteri Ekstrak Teripang Holothuria edulis Yang Diperoleh Dari Teluk Manado’, Pharmacon, 6(4), pp. 44–54.
Meyer, B. et al. (1982) ‘Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents’, Planta Medica, 45(5), pp. 31–34.

Molyneux, P. (2004) ‘The Use of the Stable Free Radical Diphenylpicryl-hydrazyl (DPPH) for Estimating Antioxidant Activity’, Songklanakarin Journal of Science and Technology, 26, pp. 211–219. doi: 10.1287/isre.6.2.144.

Moshi, M. J. et al. (2010) ‘Brine shrimp toxicity of some plants used as traditional medicines in Kagera Region, north western Tanzania’, Tanzania Journal of Health Research, 12(1), p. 7. doi: 10.4314/thrb.v12i1.56287.

Tamokou, J. de D. et al. (2012) ‘Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae)’, BMC Complementary and Alternative Medicine, 12. doi: 10.1186/1472-6882-12-99.